E3 Ligase Ligand-Linker Conjugates Inhibitors

von Hippel-Lindau (VHL)

MDM2

Cereblon

cIAP1

Aryl Hydrocarbon Receptor

TRIM21

E3 Ligase Ligand-Linker Conjugates

Product Name	von Hippel-Lindau (VHL)	MDM2	Cereblon	cIAP1	Aryl Hydrocarbon Receptor	TRIM21	Purity
(S,R,S)-AHPC-PEG5-COOH	VHL						99.80%
(S,R,S)-AHPC-PEG4-N3	VHL						99.93%
(S,R,S)-AHPC-PEG3-N3	VHL						99.67%
Thalidomide-NH-CH2-COOH			Cereblon				98.17%
(S,R,S)-AHPC-PEG3-NH2 hydrochloride	VHL						99.01%
Pomalidomide-PEG1-C2-N3			Cereblon				99.91%
(S,R,S)-AHPC-PEG1-N3	VHL						98.18%
Thalidomide-O-PEG4-NHS ester			Cereblon
BODIPY FL thalidomide			Cereblon				99.20%
(S,R,S)-AHPC-PEG4-NH2	VHL						99.51%
(S,R,S)-AHPC-PEG2-NH2 hydrochloride	VHL						99.77%
(S,R,S)-AHPC-PEG2-N3	VHL						99.74%
Lenalidomide-C5-NH2 hydrochloride			Cereblon				98.44%
VH032-PEG3-acetylene	VHL						98.14%
Thalidomide-O-amido-PEG4-azide			Cereblon				99.19%
(S,R,S)-AHPC-amido-C5-acid	VHL						99.58%
Pomalidomide-PEG4-azide			Cereblon				99.85%
Pomalidomide-PEG4-C-COOH			Cereblon				99.10%
Pomalidomide-C2-NH2 hydrochloride			Cereblon				99.46%
Pomalidomide 4'-alkylC5-acid			Cereblon				98.78%
Thalidomide-O-PEG2-propargyl			Cereblon				98.26%
Thalidomide-4-O-C6-NH2 hydrochloride			Cereblon				98.53%
Pomalidomide-PEG2-azide			Cereblon
A 410099.1, amine-Boc hydrochloride				cIAP1
Pomalidomide 4'-PEG5-acid			Cereblon
Thalidomide-O-C8-COOH			Cereblon
Pomalidomide-PEG3-azide			Cereblon				98.88%
Thalidomide-O-C2-acid			Cereblon
Thalidomide-O-amido-C3-COOH			Cereblon				98.43%
Thalidomide-PEG2-C2-NH2 hydrochloride			Cereblon				99.89%
Pomalidomide-C7-COOH			Cereblon				98.07%
Pomalidomide 4'-PEG3-azide			Cereblon
Pomalidomide-PEG4-C2-NH2 hydrochloride			Cereblon
Pomalidomide-PEG1-C2-COOH			Cereblon				99.76%
Thalidomide-O-C6-COOH			Cereblon				99.67%
(S,R,S)-AHPC-PEG4-NH2 hydrochloride	VHL						98.06%
Biotin-PEG6-Thalidomide			Cereblon				98.51%
Pomalidomide-PEG3-C2-NH2 TFA			Cereblon				99.0%
Lenalidomide-propargyl-C2-NH2 hydrochloride			Cereblon				98.04%
(S,R,S)-AHPC-C2-NH2 dihydrochloride	VHL						98.63%
Nutlin-C1-amido-PEG4-C2-N3		MDM2					99.19%
(S,R,S)-AHPC-C8-NH2	VHL
Thalidomide-NH-PEG3-propionic acid			Cereblon				99.72%
Thalidomide-O-C5-acid			Cereblon
Pomalidomide-amido-C3-COOH			Cereblon				99.51%
Pomalidomide-amino-PEG3-NH2 hydrochloride			Cereblon				99.52%
Thalidomide-O-amido-C4-N3			Cereblon				98.36%
Lenalidomide-acetylene-C5-COOH			Cereblon				99.26%
Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride			Cereblon
Thalidomide-NH-C5-NH2 hydrochloride			Cereblon				99.28%
(S,R,S)-AHPC-Me-C5-COOH	VHL
Thalidomide-NH-PEG4-COOH			Cereblon				98.55%
Pomalidomide-amido-PEG3-C2-NH2			Cereblon				99.55%
Thalidomide-4-O-C5-NH2 hydrochloride			Cereblon
(S,R,S)-AHPC-C3-NH2 hydrochloride	VHL
Pomalidomide-amino-PEG5-NH2 hydrochloride			Cereblon				99.58%
(S,R,S)-AHPC-(C3-PEG)2-C6-Cl	VHL						99.89%
Thalidomide-PEG2-C2-NH2 TFA			Cereblon				99.39%
Thalidomide-O-C8-Boc			Cereblon
(S,R,S)-AHPC-C4-NH2 dihydrochloride	VHL
Thalidomide-O-amido-C4-NH2 hydrochloride			Cereblon				98.11%
Thalidomide-Piperazine-PEG1-COOH			Cereblon				99.24%
Thalidomide-Piperazine-PEG3-COOH			Cereblon				99.89%
Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride			Cereblon				98.29%
(S,R,S)-AHPC-Me-CO-CH2-PEG3-NH2	VHL
Thalidomide-PEG3-COOH			Cereblon				98.05%
Thalidomide-NH-PEG2-COOH			Cereblon				98.65%
Thalidomide-O-amido-PEG-C2-NH2 hydrochloride			Cereblon				98.10%
(S,R,S)-AHPC-C6-NH2	VHL						98.03%
Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH			Cereblon
Pomalidomide-C3-NHS ester			Cereblon				98.70%
Thalidomide-NH-C10-COOH			Cereblon
Thalidomide-propargyl			Cereblon				99.97%
Thalidomide-O-PEG4-azide			Cereblon				98.03%
Thalidomide-PEG2-NH2 hydrochloride			Cereblon
Lenalidomide-C4-NH2 hydrochloride			Cereblon				98.85%
Thalidomide-5-PEG4-NH2 hydrochloride			Cereblon
Thalidomide-4-O-C2-NH2 hydrochloride			Cereblon				99.37%
Pomalidomide-C12-NH2 hydrochloride			Cereblon
Thalidomide-O-amido-C3-NH2 TFA			Cereblon				99.58%
Thalidomide-O-amido-C6-NH2 TFA			Cereblon				99.82%
(S,R,S)-AHPC-PEG5-Boc	VHL
(S,R,S)-AHPC-PEG3-propionic acid	VHL
Thalidomide-NH-C6-NH-Boc			Cereblon
Thalidomide-O-amido-PEG2-C2-NH2 TFA			Cereblon				99.72%
Thalidomide-O-amido-C4-NH2			Cereblon
Lenalidomide-propargyl-C2-amido-Ph-NH2 hydrochloride			Cereblon
Thalidomide-4-O-C4-NH2 hydrochloride			Cereblon				99.35%
Thalidomide-Piperazine-PEG1-NH2			Cereblon
Thalidomide-NH-C6-NH2 TFA			Cereblon				99.82%
Thalidomide-NH-PEG2-C2-NH-Boc			Cereblon				98.37%
Thalidomide-PEG4-NH2 hydrochloride			Cereblon
Thalidomide-O-amido-C3-PEG3-C1-NH2			Cereblon				99.08%
Thalidomide-O-amido-PEG3-C2-NH2			Cereblon
Pomalidomide-PEG6-NH2 hydrochloride			Cereblon				98.01%
Thalidomide-Piperazine-PEG2-NH2			Cereblon
Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 TFA			Cereblon				99.28%
(S,R,S)-AHPC-Me-C10-Br	VHL
Thalidomide-NH-PEG3-COOH			Cereblon				98.90%
Pomalidomide-amido-C1-Br			Cereblon
Thalidomide-PEG5-COOH			Cereblon				98.09%
Thalidomide-Propargyne-PEG1-COOH			Cereblon				99.62%
Thalidomide-Propargyne-PEG3-COOH			Cereblon				98.01%
(S,R,S)-AHPC-PEG3-NH2	VHL						99.26%
(S,R,S)-AHPC-C6-NH2 hydrochloride	VHL
Pomalidomide-PEG6-butyl iodide			Cereblon				98.35%
(S,R,S)-AHPC-PEG2-NH2	VHL
Pomalidomide-PEG4-C2-NH2			Cereblon
(S,R,S)-AHPC-O-Ph-PEG1-NH2	VHL
Thalidomide-piperazine-Boc			Cereblon				98.82%
Thalidomide-Propargyne-PEG2-COOH			Cereblon				99.07%
Thalidomide-PEG4-COOH			Cereblon
(S,R,S)-AHPC-PEG2-NH2 dihydrochloride	VHL
(S,R,S)-AHPC-C8-NH2 hydrochloride	VHL
Thalidomide-Piperazine-PEG2-COOH			Cereblon				99.79%
Glutarimide-Isoindolinone-NH-PEG2-COOH			Cereblon				98.51%
Thalidomide-5-CH2-NH2 hydrochloride			Cereblon				98.55%
Thalidomide-4-O-C8-NH2 hydrochloride			Cereblon
Thalidomide-Piperazine-Piperidine hydrochloride			Cereblon				98.73%
Thalidomide-PEG5-NH2 hydrochloride			Cereblon
Pomalidomide-PEG3-C2-NH2			Cereblon
Pomalidomide-PEG3-C2-NH2 hydrochloride			Cereblon
(S,R,S)-AHPC-C1-Br	VHL						≥98.0%
Thalidomide-NH-PEG3-NH-Boc			Cereblon
Thalidomide-C2-amido-C2-COOH			Cereblon
Thalidomide-Piperazine-PEG1-NH2 diTFA			Cereblon				99.43%
(S,R,S)-AHPC-C4-NH2 hydrochloride	VHL
Thalidomide-O-amido-C8-NH2 TFA			Cereblon				99.43%
Pomalidomide-amino-PEG4-NH2			Cereblon
Thalidomide-NH-PEG1-NH2 hydrochloride			Cereblon				99.59%
Pomalidomide-C4-NH2 hydrochloride			Cereblon				99.24%
Thalidomide-4-O-C10-COOH			Cereblon				99.14%
Thalidomide-O-PEG4-amine			Cereblon
Thalidomide-NH-C8-NH2 hydrochloride			Cereblon
Pomalidomide-PEG4-Ph-NH2			Cereblon				≥98.0%
Thalidomide-O-PEG4-amine hydrochloride			Cereblon
Lenalidomide-C5-amido-Boc			Cereblon
Thalidomide-5-PEG3-NH2 hydrochloride			Cereblon
Thalidomide-4-O-C3-NH2 hydrochloride			Cereblon
Thalidomide-NH-C6-NH2 hydrochloride			Cereblon				99.62%
Glutarimide-Isoindolinone-NH-PEG4-COOH			Cereblon				99.52%
Thalidomide-O-amido-PEG3-C2-NH2 TFA			Cereblon				99.55%
Thalidomide-O-C6-azide			Cereblon				99.71%
Thalidomide-O-C6-NHBoc			Cereblon
Glutarimide-Isoindolinone-NH-PEG3-COOH			Cereblon				99.12%
Thalidomide-Piperazine 5-fluoride			Cereblon
Thalidomide-PEG4-Propargyl			Cereblon
Pomalidomide-C3-NH2 hydrochloride			Cereblon
Pomalidomide-amino-PEG4-NH2 hydrochloride			Cereblon				99.27%
Thalidomide-O-amido-C4-NH2 TFA			Cereblon				99.92%
Thalidomide-Piperazine-PEG2-NH2 diTFA			Cereblon				99.73%
(S,R,S)-AHPC-C10-NH2	VHL
Thalidomide-PEG5-NH2			Cereblon
Thalidomide-5-PEG3-NH2			Cereblon
Lenalidomide-PEG3-iodine			Cereblon
Thalidomide-PEG3-NH2			Cereblon
Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2			Cereblon
Thalidomide-4-O-C7-NH2			Cereblon
Thalidomide-NH-C4-NH2 TFA			Cereblon
Thalidomide-O-amido-C3-NH2			Cereblon
Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride			Cereblon
cIAP1 Ligand-Linker Conjugates 1				cIAP1
Thalidomide-NH-PEG7			Cereblon
Thalidomide-O-amido-C8-NH2 hydrochloride			Cereblon
Thalidomide-Piperazine-PEG3-NH2			Cereblon
Thalidomide-PEG2-C2-NH2			Cereblon
(S,R,S)-AHPC-C3-NH2 TFA	VHL
Thalidomide-O-amido-PEG-C2-NH2			Cereblon
Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride			Cereblon
Thalidomide-4-O-C6-NH2 TFA			Cereblon
Thalidomide-O-amide-C5-NH2 TFA			Cereblon
Thalidomide-4-O-C10-NH2			Cereblon
Thalidomide-NH-PEG4-MS			Cereblon
Thalidomide-4-O-C6-NH2			Cereblon
Thalidomide-PEG2-NH2			Cereblon
Thalidomide-O-amido-C6-NH2			Cereblon
Thalidomide-5-PEG4-NH2			Cereblon
Thalidomide-4-O-C8-NH2			Cereblon
Thalidomide-O-C3-acid			Cereblon
Thalidomide-NH-C6-NH2			Cereblon
Thalidomide-Piperazine-Piperidine			Cereblon
Thalidomide-O-amido-PEG2-C2-NH2			Cereblon
Thalidomide-O-amide-C5-NH2			Cereblon
Lenalidomide-C5-NH2 TFA			Cereblon				98.94%
Thalidomide-NH-C2-PEG3-OH			Cereblon
(S,R,S)-AHPC-C10-NH2 dihydrochloride	VHL
(S,R,S)-AHPC-C6-NH2 dihydrochloride	VHL
(S,R,S)-AHPC-PEG1-NH2 dihydrochloride	VHL
(S,R,S)-AHPC-C5-COOH	VHL						98.81%
(S,R,S)-AHPC-C8-NH2 dihydrochloride	VHL
Thalidomide-O-amido-PEG4-C2-NH2			Cereblon
Pomalidomide-PEG2-Tos			Cereblon
(S,R,S)-AHPC-C3-NH2	VHL
(S,R,S)-AHPC-PEG1-OTs	VHL
(S,R,S)-AHPC-C4-NH2	VHL
Thalidomide-NH-C4-NH-Boc			Cereblon				99.64%
Pomalidomide-amido-C3-piperazine-N-Boc			Cereblon
VHL Ligand-Linker Conjugates 15	VHL
(S,R,S)-AHPC-Me-C10-NH2	VHL
Pomalidomide-amido-C4-amido-C6-NH-Boc			Cereblon
Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc			Cereblon
Pomalidomide-amino-PEG5-NH2			Cereblon
cIAP1 Ligand-Linker Conjugates 13				cIAP1
cIAP1 Ligand-Linker Conjugates 15 hydrochloride				cIAP1
(S,R,S)-AHPC-C7-amine	VHL
Thalidomide-O-amido-PEG4-propargyl			Cereblon
Thalidomide-5-NH-PEG2-NH2 hydrochloride			Cereblon
Thalidomide-4-O-C2-NH2			Cereblon
Thalidomide-NH-amido-PEG3-C2-NH2 hydrochloride			Cereblon
Thalidomide-5-propargyne-NH2 hydrochloride			Cereblon
cIAP1 Ligand-Linker Conjugates 14				cIAP1
Thalidomide-PEG3-NH2 hydrochloride			Cereblon				98.02%
Thalidomide-O-C3-NH2			Cereblon
A 410099.1 amide-PEG3-amine-Boc				cIAP1
VHL Ligand-Linker Conjugates 17	VHL
Pomalidomide-C3-NH2			Cereblon
Thalidomide-amido-PEG2-NH2 hydrochloride			Cereblon
Thalidomide-NH-PEG1-NH2 diTFA			Cereblon
Thalidomide-NH-amido-PEG3-C2-NH2			Cereblon
Thalidomide-NH-amido-C8-NH2			Cereblon
Thalidomide-NH-PEG8-Ts			Cereblon
Thalidomide-O-PEG4-amine TFA			Cereblon
Thalidomide-NH-amido-PEG1-C2-NH2 hydrochloride			Cereblon
Thalidomide-NH-C5-NH2			Cereblon
AhR Ligand-Linker Conjugates 1					Aryl Hydrocarbon Receptor
Pom-8PEG			Cereblon
Amino-PEG6-Thalidomide			Cereblon
cIAP1 Ligand-Linker Conjugates 2 Hydrochloride				cIAP1
(S,R,S)-AHPC-C5-NH2	VHL
N-Boc-SBP-0636457-O-C3-COOH				cIAP1
Thalidomide-N-C3-O-C4-O-C3-OH			Cereblon
Thalidomide-NH-amido-C2-NH2 hydrochloride			Cereblon
Pomalidomide-amino-PEG3-NH2			Cereblon
cIAP1 Ligand-Linker Conjugates 3				cIAP1
Lenalidomide-C5-acid			Cereblon
Thalidomide-O-C4-NH2			Cereblon
(S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH	VHL						99.31%
Thalidomide-Piperazine 5-fluoride hydrochloride			Cereblon
Thalidomide-NH-amido-PEG2-C2-NH2 hydrochloride			Cereblon
cIAP1 Ligand-Linker Conjugates 10				cIAP1
VH032-thiol-C6-NH2	VHL
Thalidomide-NH-amido-C4-NH2 hydrochloride			Cereblon
Pomalidomide-C6-NHS ester			Cereblon
(S,R,S)-AHPC-PEG1-NH2	VHL
Thalidomide-4-O-C5-NH2			Cereblon
Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc			Cereblon
A 410099.1 amide-PEG2-amine-Boc				cIAP1
Thalidomide-NH-amido-C4-NH2			Cereblon
Thalidomide-NH-amido-C3-NH2 hydrochloride			Cereblon
Thalidomide-O-amido-C6-NH2 hydrochloride			Cereblon				99.32%
Thalidomide-NH-amido-C3-NH2			Cereblon
Thalidomide-4-NH-PEG1-NH2 TFA			Cereblon
cIAP1 Ligand-Linker Conjugates 11 Hydrochloride				cIAP1
Thalidomide-O-C7-acid			Cereblon				98.55%
Thalidomide-O-C4-COOH			Cereblon
Thalidomide-amido-PEG2-NH2			Cereblon
Thalidomide-4-O-CH2-COO(t-Bu)			Cereblon
Thalidomide-NH-amido-C5-NH2			Cereblon
Thalidomide-NH-(CH2)2-NH2 TFA			Cereblon
cIAP1 Ligand-Linker Conjugates 15				cIAP1
cIAP1 Ligand-Linker Conjugates 9				cIAP1
A 410099.1, amine-Boc				cIAP1
cIAP1 Ligand-Linker Conjugates 11				cIAP1
(S,R,S)-AHPC-C2-NH2	VHL
Thalidomide-NH-amido-C6-NH2			Cereblon
(S,R,S)-AHPC-C1-NH2 hydrochloride	VHL						98.08%
Thalidomide-4-C3-NH2 hydrochloride			Cereblon
cIAP1 Ligand-Linker Conjugates 12				cIAP1
Thalidomide-NH-amido-PEG1-C2-NH2			Cereblon
Thalidomide-NH-CH2-COO(t-Bu)			Cereblon
(S,R,S)-AHPC-C1-NH2	VHL
Boc-A 410099.1 amide-alkylC4-amine				cIAP1
Thalidomide-NH-C8-NH2			Cereblon
Thalidomide-NH-amido-C8-NH2 hydrochloride			Cereblon
Thalidomide-NH-amido-PEG2-C2-NH2			Cereblon
Thalidomide-NH-PEG1-NH2			Cereblon
Thalidomide-O-C11-acid			Cereblon
Thalidomide-NH-amido-PEG4-C2-NH2 hydrochloride			Cereblon
Thalidomide-O-PEG4-Boc			Cereblon
cIAP1 Ligand-Linker Conjugates 8				cIAP1
Thalidomide-NH-amido-C5-NH2 hydrochloride			Cereblon
cIAP1 Ligand-Linker Conjugates 7				cIAP1
Thalidomide-NH-amido-PEG4-C2-NH2			Cereblon
Pomalidomide-cyclopentane-amide-Alkyne			Cereblon
cIAP1 Ligand-Linker Conjugates 5				cIAP1
Thalidomide-NH-amido-C2-NH2			Cereblon
(S,R,S)-AHPC-C2-PEG4-N3	VHL
cIAP1 Ligand-Linker Conjugates 4				cIAP1
Thalidomide-5-propoxyethanamine			Cereblon
cIAP1 Ligand-Linker Conjugates 2				cIAP1
Pomalidomide-C4-NH2			Cereblon
Thalidomide-5-PEG2-Cl			Cereblon
Thalidomide-NH-amido-C6-NH2 hydrochloride			Cereblon
Acepromazine-1-Piperazinepropanamine						TRIM21
cIAP1 Ligand-Linker Conjugates 6 hydrochloride				cIAP1
Pomalidomide 4'-PEG6-azide			Cereblon
Thalidomide-piperazine-piperidine-2-F-Ph-CHO			Cereblon
Pomalidomide-C2-acid			Cereblon
Pomalidomide-PEG2-OH			Cereblon
Pomalidomide-PEG3-OH			Cereblon
Thalidomide 4'-oxyacetamide-C1-PEG3-C3-amine hydrochloride			Cereblon
Thalidomide-O-amido-C8-NH2			Cereblon

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